Marija Cvetanovic, PhD

Assistant Professor, Department of Neuroscience

Marija Cvetanovic

Contact Info

mcvetano@umn.edu

Office Phone 612-626-4918

Office Address:
3-116 WMBB

Lab Address:
3-200 WMBB

Assistant Professor, Department of Neuroscience


Research

Research Summary/Interests

Glial Cells in Neurodegenerative Disease

Our lab aims to understand how different brain cells and their interactions influence the onset and progression of neurodegenerative diseases. In particular we study the involvement of astrocytes and microglia in the pathogenesis of inherited neurodegenerative disease Spinocerebellar ataxia type 1(SCA1). SCA1 belongs to the family of polyglutamine diseases, that include Huntington’s disease as it is caused by the expansion of CAG repeat (encoding for glutamine) in the coding region of Ataxin-1 gene. To do this we are using mouse genetics, cell and molecular biology techniques, mouse behavior, confocal microscopy and flow cytometry. The ultimate goal is to increase knowledge of the cellular and molecular pathways that underlie pathology of neurodegenerative disorders and open new avenues for therapeutic approaches. Another main focus of the lab is to train the next generations of scientists by creating the supportive environment that is conductive to learning, creating and testing new ideas.

Publications

For a list of publications, see PubMed.

Teaching

Courses

NSCI 4105: Neurobiology Laboratory I (Fall and Summer semesters)