S. Hossein Fatemi, MD, PhD

Professor, Department of Psychiatry

S. Hossein Fatemi

Contact Info


Office Phone 612-626-3633

Office Address:
392 MMC

MD, Case Western Reserve University

Residency, Psychiatry, University Hospitals, Cleveland, OH

PhD, Anatomy, University of Nebraska Medical Center

MS, Anatomy, University of Nebraska Medical Center

BS, Biology, Baylor University

Internship, Diagnostic Radiology at University of Cincinnati Hospital, 1991-1992


Dr. Fatemi is the Associate Chair for Neuroscience and Translational Research for the Department of Psychiatry; the Bernstein Endowed Chair in Adult Psychiatry; Professor of Psychiatry, Neuroscience and Pharmacology, at the University of Minnesota Medical School. Dr. Fatemi’s research interests include the molecular causes and the biological basis of neurodevelopmental disorders, primarily schizophrenia and autism. His clinical interests include treatment and psychopharmacology of major depression, bipolar disorder, and schizophrenia. He has over 18 years experience in the treatment of psychiatric disorders. Dr. Fatemi is a member of the American College of Psychiatrists, a Fellow the American College of Neuropsychopharmacology, and International College of Neuropsychopharmacology, and a Distinguished Fellow of the American Psychiatric Association.

Professional Associations

  • Associate Chair for Neuroscience and Translational Research


Research Summary/Interests

Molecular causes of schizophrenia and autism

Dr. Fatemi's research and clinical interests have focused on the etiology and treatment of schizophrenia and mood disorders. His primary research interests include molecular causes and studies of the biological basis of schizophrenia and autism. He is an attending physician at the University Hospital CL Service working with psychiatry residents in their training. Dr. Fatemi has a NARSAD established investigator award, a Stanley Foundation award and a Minnesota Medical foundation grant for the investigation of the expression of several proteins in mouse hippocampus following prenatal exposure to influenza and mapping of the same proteins in the postmortem brains of patients with schizophrenia. His latest publications include articles in Molecular Psychiatry, Synapse and Brain Research describing his data involving prenatal viral infection in mice.

Fig. 2. (above) Concentrations and gel mobilities for Reelin, albumin and ceruloplasmin in controls, schizophrenics, and subjects with bipolar disorder and major depression. SDS-PAGE and western blotting of serum proteins from representative normal control (C3, C5, C6, C7), schizophrenic (S3, S9, S10, S15), bipolar (B4, B5) and depressed (D1, D3) subjects are shown. The upper panel demonstrates three Reelin bands at 410, 330 and 180 kDa. The middle and lower panel blot patterns represent 30 and 5 g unpurified serum ceruloplasmin and albumin species per corresponding subject serum subjected to SDS-PAGE and Western blotting.


For a list of publications, see PubMed.


Board Certifications

  • Adult psychiatry, Diplomate of American Board of Psychiatry and Neurology
  • Psychosomatic medicine, Diplomate of American Board of Psychiatry and Neurology